Chelsea face Barcelona in the second leg of the last-16 UCL encounter, and are looking to progress after a 1-1 draw at home.
Should Fabregas play, he will find himself in the same space as Messi, and he hopes to be a stumbling block to him.
“If I am lucky enough to play, it’s true that we are positioned in nearby areas of the pitch, stopping him will be difficult but I will try to do everything possible so that he feels uncomfortable and can’t put together a perfect performance,” he told Marca.
“I see him as a rival who wants to win, and I want the same thing. We are in different teams and each player wants what is best for their own club. Obviously, you always have respect for each other.”
“It’s difficult as the Camp Nou is very big and you have to run a lot, but we’ll work together,” he said. “The key is to take advantage of our opportunities, we have to play our game but do damage when possible.
“I’ve never trained tactically as much as I have at Chelsea and it shows on the pitch. It’s demanding but we end up benefitting from it.”